Basic obstetric pharmacology

Basic and Ocular Pharmacology BASIC AND OCULAR PHARMACOLOGY

Introduction The science of pharmacology is concerned with the effects of drugs on the function of living tissues (Greek: Pharmakos = drug, Logos = study). Since modern medicine relies heavily on drugs as the principal tool for the treatment and prevention of disease, it is important that all clinicians possess a basic understanding of the pharmacological principles that govern their clinical u...

Obstetric Therapeutics; Clinical Pharmacology and Therapeutics in Obstetric Practice

Basic opioid pharmacology: an update.

Opioids are a group of analgesic agents commonly used in clinical practice. There are three classical opioid receptors (DOP, KOP and MOP), while the novel NOP receptor is considered to be a non-opioid branch of the opioid receptor family. Opioids can act at these receptors as agonists, antagonists or partial agonists. Opioid agonists bind to G-protein coupled receptors to cause cellular hyperpo...

The grand challenges in obstetric and pediatric pharmacology

Obstetric and pediatric pharmacology urgently need creative, collaborative, multidisciplinary research approaches to optimize medication use in these vulnerable patient populations. Optimal use of medications in these populations, in order to provide greater understanding and confidence for both patients and caregivers, and training the next generation of pediatric and obstetric pharmacologists...

International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology.

Orexin signaling is essential for normal regulation of arousal and behavioral state control and represents an attractive target for therapeutics combating insomnia. Alternatively termed hypocretins, these neuropeptides were named to reflect sequence similarity to incretins and their potential to promote feeding. Current nomenclature reflects these molecular and biochemical discovery approaches ...